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LPC OMe LPC LPC and OMe LPC were
2022-06-23

LPC 14:0, 2-OMe-LPC 14:0, LPC 16:0 and 2-OMe-LPC 16:0 were shown to be most potent stimulators of intracellular calcium flux in the β cell model, which is one of key processes leading to insulin exocytosis. Yet, species with myristoyl residue initiate calcium influx through voltage-gated 9-amino Cam
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Thyroid hormone triiodothyronine T and its precursor
2022-06-23

Thyroid hormone 3,5,3′-triiodothyronine (T3) and its precursor, thyroxine (T4), are iodinated compounds, which are known to regulate the expression of genes involved in various biological processes, such as development, growth and metabolic control. The iodothyronine deiodinase types I, II and III (
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br Materials and methods br Results
2022-06-23

Materials and methods Results Discussion Nervous system disease is an important signal of AIDS deterioration (Rosca et al., 2012, Yilmaz et al., 2012). It is possible that HIV crosses the blood NG25 barrier or blood cerebrospinal fluid barrier into the central nervous system freely or via
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Obestatin increased GnRH mRNA expression in the POA being
2022-06-23

Obestatin increased GnRH mRNA expression in the POA, being the main place of GnRH synthesis (Goodman, 2015). Simultaneously, obestatin also caused a decrease in the GnRH mRNA expression in ME, without affecting the level of this peptide mRNA in AHA. A lack of differences observed in the mRNA level i
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The HRTOF MS of showed a quasi molecular ion peak
2022-06-23

The HRTOF-MS of showed a quasi-molecular ion peak at / 525.3044 [M+Na], corresponding to a quasi-molecular formula of CHNONa (Calcd for CHNONa: 525.3053). IR absorptions at 1680 and 1522cm suggested the presence of amide functions. Based on an analysis of 1D and 2D NMR spectra, the presence of one
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ahr pathway Ginger derived glycoproteins contain a
2022-06-23

Ginger-derived ahr pathway contain a variety of functional components, including specific phenolic compounds, purine compounds, and bioactive polysaccharides. Moreover, glycoproteins belong to the glycoconjugates, which combine some of the properties of polysaccharides and proteins. It has been repo
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The neuronal glycine receptor HSOR allopregnanolone pathway
2022-06-23

The neuronal glycine receptor/3α-HSOR/allopregnanolone pathway may also be extended to the central nervous effects of gelsemine and koumine in brain. 3α-HSOR is expressed in certain brain regions in rats and humans, such as the limbic system including hypothalamus, hippocampus and amygdala, in addit
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br Introduction L Glutamate is one
2022-06-23

Introduction L-Glutamate is one of the most prevalent excitatory signaling molecules in the central nervous system (CNS) (Salazar et al., 2016) and plays a crucial role in a variety of monensin functions such as memory and learning (Danbolt, 2001, Nedergaard et al., 2002). At elevated concentrat
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Prior to cellular uptake studies
2022-06-23

Prior to cellular uptake studies of PF-03814735 receptor , docking simulation was performed (A). The result suggested this complex was capable of binding in the cavity of an outward open XylE. The orientation of the sugar moiety in the docked complex was similar to that of the glucose unit bound in
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Capecitabine sale To evaluate SLC A abundance after transfec
2022-06-23

To evaluate SLC45A1 abundance after transfection, we performed western blots. Transfected COS-7 Capecitabine sale were lysed and separated for membrane fraction. Equal amounts of proteins from membrane fractions were resolved by SDS-PAGE, transferred to a nitrocellulose filter, and immunoblotted wi
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Acknowledgments br Introduction Type diabetes mellitus T DM
2022-06-23

Acknowledgments Introduction Type 2 diabetes mellitus (T2DM) is caused by relative insulin deficiency or insulin resistance in peripheral tissues. The clinical management of T2DM is achieved by controlling blood glucose levels. Current therapies available for treatment of T2DM include biguanides
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br Methods br Results br Discussion In
2022-06-22

Methods Results Discussion In this study, we investigated temperature effects on Vj-gating properties of two cardiac GJs. In the case of Cx45 GJs, increased temperature from 22 °C to 28 °C (or 32 °C) led to an accelerated Vj-dependent deactivation with little change in the extent of Vj-gati
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All of the abovementioned effects of PUFAs signal their invo
2022-06-22

All of the abovementioned effects of PUFAs signal their involvement in a cellular phenotype switching phenomenon, which is increasingly recognized as a potential target for future pharmacotherapies of atherosclerosis, especially for individuals who do not respond to the classical lipid-lowering str
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We have presented evidence that only muscle FBPase is
2022-06-22

We have presented evidence that only muscle FBPase is detectable within HL-1 cells. This is consistent with past findings of the Eschrich's group, which showed that in rat heart Fisetin expression of FBPase is almost exclusively limited to the muscle isozyme [3]. Results of our preliminary experim
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Bilirubin In analyzed alleles in this
2022-06-22

In 3/11 analyzed Bilirubin in this study, the c.472C>T missense variant was detected. This variant was previously reported in Malaysian, French, Indian and Pakistani patients (Bhai et al., 2018; Ijaz et al., 2017; Lebigot et al., 2015; Moey et al., 2018; Ngu et al., 2014) who were homozygous and co
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