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Similar to the importance of MeJA in postharvest A bisporus
2024-12-24
Similar to the importance of MeJA in postharvest A. bisporus quality maintenance at 10°C storage (Meng et al., 2012a), MeJA was also observed to play a pivotal role in this event at 4°C storage. Cap opening is an important mushroom quality indicator (Braaksma et al., 1999). During postharvest storag
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Once apoptosis has been initiated the
2024-12-24
Once apoptosis has been initiated the HMGA proteins themselves undergo marked changes in both the types and extent of their post-translational modifications (PTMs; review in [149,175]), some of which are likely correlated with alterations in chromatin structure. For example, the early stages of apop
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br Acknowledgments br Protein microarrays were developed
2024-12-24
Acknowledgments Protein microarrays were developed to provide miniaturized high-throughput tools to study protein function, Gambogic Acid and post-translational modifications. Just a few years ago, the seminal work performed in Stuart Schreiber's laboratory at Harvard University () and at Mich
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It is noteworthy that in
2024-12-24
It is noteworthy that in both cases there is a higher risk for prematurity [44], [61], [97], [98] and for deliveries of newborn small for GA [89], [95], [97], [98]. sFlt-1:PlGF has been showed to be inversely correlated with GA at birth, since 86% of pregnant women who gave birth at CI 976 of rs476
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br Materials and Methods br Results A total of NSCLC
2024-12-24
Materials and Methods Results A total of 28 NSCLC tumor samples from 26 patients (2 patients with paired tumor samples) were included. According to the initial FISH (Abbott Molecular probes) and IHC results, 13 samples were ALK IHC+FISH+, 5 samples were ALK IHC+FISH−, 2 samples (from the same
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To investigate further the clinical
2024-12-24
To investigate further the clinical and mutational spectrum associated with -related dyskinesia, we here performed a screen in a large series of patients affected with an unexplained hyperkinetic movement disorder, resulting in the identification of 2 pediatric patients presenting with a novel pheno
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A similar circuit between pyramidal
2024-12-23
A similar circuit between pyramidal neurons and SST interneurons is also prevalent in layers 2/3 of the cortex. The synapses onto SST interneurons, however, are functionally weak, raising questions about their computational power. In the first set of experiments, Urban-Ciecko et al. (2018) show that
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However for a molecular target to
2024-12-23
However, for a molecular target to be useful in AD, it must rescue behavioral as well as biochemical insults. In humans, AD memory impairments typically declare themselves initially as disruption of episodic memory and consolidation of new memories, eventually progressing to global cognitive decline
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Another contributor for the G M arrest in
2024-12-23
Another contributor for the G2/M arrest in A549 and H1299 cells might be p21WAF1/CIP1 which was up-regulated upon ovatodiolide treatment. p21WAF1/CIP1 is a common CDKs inhibitor which blocks tebuconazole metabolites G2/M phase progression in various types of cancer cells (Kim et al., 2015, Liberio e
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br Introducing toll like receptors TLRs are the
2024-12-23
Introducing toll like receptors TLRs are the most important receptors which are expressed on the cytoplasmic and internal vesicles membrane. They have a similar structure including a leucine-rich repeats (LRRs) domain which is out of elastase inhibitor membrane, a hydrophobic transmembrane and a
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Apoptosis signal regulating kinase ASK
2024-12-23
Apoptosis signal-regulating kinase 1 (ASK1, also referred to as MAP3K5)(Ichijo et al., 1997) participates in many different stress responses, including apoptosis (Chang et al., 1998, Chen et al., 1999, Ichijo et al., 1997, Kanamoto et al., 2000, Noguchi et al., 2008, Saitoh et al., 1998, Tobiume et
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The alamarBlue test revealed that recombinant apelin led to
2024-12-23
The alamarBlue test revealed that recombinant apelin led to an increase in basal and IGF1- and FHS-induced ovarian cell proliferation. Apelin increased ERK1/2 and Akt protein expression, but cell proliferation returned to control levels in the presence of kinase inhibitors. This suggests that the pr
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br Conflict of interest br
2024-12-23
Conflict of interest Acknowledgments This work was financially supported by the Fund Project of Sichuan Provincial Department of Education (16ZB0053), the Scientific Research Foundation of Sichuan Agricultural University (No. 06021400) and the China Postdoctoral Science Foundation (No. 2015M58
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To circumvent these issues multiple approaches have been dev
2024-12-23
To circumvent these issues, multiple approaches have been developed that target small fractions of the genome, thus reducing the sequencing burden (Dostie et al., 2006; Fullwood et al., 2009; Mumbach et al., 2016). Application of one such approach, chromosome conformation capture carbon copy (5C), w
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Although the interactions of PhLP with G
2024-12-23
Although the interactions of PhLP with Gβγ and its other partners have been convincingly documented through in vitro studies, it is not clear how PhLP controls LP533401 hcl signaling in vivo. C. elegans provides a powerful genetic model to analyze Phosducin function and study its interacting partne
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